The comparative pathology laboratory is the critical support element of the veterinary medicine vivarium. Our laboratory staff leverage their expertise and our state-of-the-art equipment in maintaining the health of our animal colonies and in the characterization of our disease models.

Support Capabilities:
 

• Histology, histopathology, immunohistochemistry
• Malaria microscopy
• Clinical pathology
• Parasitology
• Endocrinology
• PCR, qPCR, ELISA, ELISpot
• Flow cytometry
• Cell culture
• Digital images: slide scans, photomicrographs, immunofluorescence

All equipment and laboratory analysis are performed in accordance with good laboratory practices. We have supported GLP studies in the past and maintain those requirements as our standard operating procedures.

We routinely apply new techniques and equipment to our support capabilities. Our staff has a combined experience of over 100 years supporting studies. Some specific examples which demonstrate our dedication and expertise include characterization of the microanatomic distribution of Orientia tsutsugamushi bacteria within the nearly microscopic chigger mite by immunofluorescence and immunohistochemistry.

In support of malaria studies, we perform thousands of time-sensitive cytology evaluations which drive the treatment decisions for animals on study. And finally, we have demonstrated the immunological profile of responses to multiple infections such as scrub typhus utilizing ELISpot and flow cytometry technologies.